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REMARK: A Number of These 9240 Excess ED Visits May Be Early Manifestations of ASIA (Autoimmune/Inflammatory Syndrome induced by Adjuvants)
By: Eric, on 12 Aug 2016

As proved in the attached proof ele148, this data represents 9240 additional ED visits beyond what is expected due to normal background rate.

As indicated in the linked paper, the girls getting HPV sometimes, for all we know quite often, go on to develop the ASIA syndrome that devastates their lives. There is no good reason to believe some or many of these additional ED visits may not be due to early indications of ASIA, as the study only reported on Venous thromboembolic events (VTE).`` ;

Severe somatoform and dysautonomic syndromes after HPV vaccination: case series and review of literature Beniamino Palmieri, Dimitri Poddighe, Maria Vadalà, Carmen Laurino, Carla Carnovale, Emilio Clementi 

First Online: 09 August 2016 DOI: 10.1007/s12026-016-8820-z

Palmieri, B., Poddighe, D., Vadalà, M. et al. Immunol Res (2016). doi:10.1007/s12026-016-8820-z



Human papilloma virus (HPV) is recognized as a major cause for cervical cancer among women worldwide. Two HPV vaccines are currently available: Gardasil® and Cervarix®. Both vaccines enclose viral antigenic proteins, but differ as to the biological systems of culture and the adjuvant components. Recently, a collection of symptoms, indicating nervous system dysfunction, has been described after HPV vaccination. We retrospectively described a case series including 18 girls (aged 12–24 years) referred to our “Second Opinion Medical Network” for the evaluation of “neuropathy with autonomic dysfunction” after HPV vaccination. All girls complained of long-lasting and invalidating somatoform symptoms (including asthenia, headache, cognitive dysfunctions, myalgia, sinus tachycardia and skin rashes) that have developed 1–5 days (n = 11), 5–15 days (n = 5) and 15–20 days (n = 2) after the vaccination. These cases can be included in the recently described immune dysfunction named autoimmune/inflammatory syndrome induced by adjuvants (ASIA). HPV vaccine, through its adjuvant component, is speculated to induce an abnormal activation of the immune system, involving glia cells in the nervous system too. Further researches should aim at defining the pathological and clinical aspects of these post-vaccination diseases and identifying a genetic background predisposing to these adverse reactions.

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Graph Last Updated: 26 May 2019
Topic Statement Status Last Changed: 10 Aug 2016